Dr. Yuvaraj Iyyappan

Dr. Yuvaraj Iyyappan
Scientist
yuvaraj[dot]i[at]icar[dot]gov[dot]in
Phone :
8861547600

Discipline: Bioinformatics

 

 

Research Interest

  • Developing Algorithms, Software tools and Data Bases, Macromolecular Crystallography, Structural Biology and Bioinformatics

 

Awards & Honors

  • Iyyappan Y, Dhayabaran V, Elayappan M, Chaudhary SK, Palaniappan C, Kanagaraj S. Functional characterization of a hypothetical protein (TTHA1873) from Thermus thermophilus. Proteins. 2023 Oct;91(10):1427-1436. doi: 10.1002/prot.26530. PMID: 37254593.

  • Cheemanapalli S, Palaniappan C, Mahesh Y, Iyyappan Y, Yarrappagaari S, Kanagaraj S. In vitro and in silico perspectives to explain anticancer activity of a novel syringic acid analog ((4-(1H-1, 3-benzodiazol-2-yl)-2, 6-dimethoxy phenol)) through apoptosis activation and NFkB inhibition in K562 leukemia cells. Comput Biol Med. 2023 Jan;152:106349. doi: 10.1016/j.compbiomed.2022.106349. PMID: 36470147.

  • Balakumaran M, Chidambaranathan P, Tej Kumar J P JP, Sirohi A, Kumar Jain P, Gaikwad K, Iyyappan Y, Rao AR, Sahu S, Dahuja A, Mohan S. Deciphering the mechanism of anhydrobiosis in the entomopathogenic nematode Heterorhabditis indica through comparative transcriptomics. PLoS One. 2022 Oct 27;17(10):e0275342. doi: 10.1371/journal.pone.0275342. PMID: 36301967; PMCID: PMC9612587.

  • Yuvaraj I, Chaudhary SK, Jeyakanthan J, Sekar K. Structure of the hypothetical protein TTHA1873 from Thermus thermophilus. Acta Crystallogr F. 2022 Sep 1;78(Pt 9):338-346. doi: 10.1107/S2053230X22008457. PMID: 36048084; PMCID: PMC9435673.

  • Vaigundan D, Yuvaraj I, Sunita P, Sekar K, Murthy MRN, Krishnaswamy PR. Structural characterization of a putative recombinant L-amino acid oxidase from Leptospira interrogans. Current Science 2022 Oct; 123(7):895-906

  • Chaudhary SK, Iyyappan Y, Elayappan M, Jeyakanthan J, Sekar K. Insights into product release dynamics through structural analyses of thymidylate kinase. Int J Biol Macromol. 2019 Feb 15;123:637-647. doi: 10.1016/j.ijbiomac.2018.11.025.  PMID: 30447376.

  • Yuvaraj I, Sridhar J, Michael D, Sekar K. PanGeT: Pan-genomics tool. Gene. 2017 Feb 5;600:77-84. doi: 10.1016/j.gene.2016.11.025.  PMID: 27851981.

Name Designation
Priyanka Kumari MSc
Muhammed Shamnas v MSc
Akash Paul MSc
Amresh Kumar JRF/SRF